I did a little browsing to dig out some of the cooler looking DVD Box sets available online. Feel free to comment on any I forgot. Enjoy!

Family Guy – The Total World Domination Collection

This Amazon-exclusive Family Guy – The Complete Collection contains every minute of Family Guy on DVD: 22 discs including over 100 episodes, loads of special features, plus Family Guy Presents: Stewie Griffin – The Untold Story and Family Guy: Blue Harvest – all in a limited edition, collectible "Stewie Head" package that’s available only on Amazon.com!

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Northern Exposure – The Complete Series

More info: Northern Exposure – Complete Series with bag

The Flintstones: The Complete Series

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Harry Potter Years 1-5 Limited Edition Gift Set

The Harry Potter Limited Edition Giftset includes Harry Potters Years 1-5, a Harry Potter DVD game Hogwarts Challenge, along with a bonus disc containing over 2 hours of enhanced content, an exclusive "Harry Potter’s Bookmark Collection", and collectible trading cards.

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Below you will find tons more:

Everybody Loves Raymond – The Complete Series

Finally, all 9 seasons – over 100 hours of Everybody Loves Raymond on 44 discs – are now available under one roof! Inside this collectible house structure are all 210 episodes, along with loads of bonus features and a 40-page script of the series finale autographed by all 10 of the episode’s writers.

More info: Everybody Loves Raymond – The Complete Series

Full House – The Complete Series Collection

More info: Full House – The Complete Series Collection

The King of Queens – The Complete Series

The hilarity of the Heffernan household entertained viewers for nine whole seasons. The popular sitcom stars Kevin James as Doug Heffernan, a delivery man who lives in Queens with his shopaholic wife Carrie (Leah Remini). The couple’s life together is turned upside down when Carrie’s eccentric father Arthur (Jerry Stiller SEINFELD) moves in with them taking over Doug’s cherished TV room and usurping his sports-watching habits. The unusual family arrangement provides laughs and challenges over the next nine eventful years.

More info: The King of Queens – The Complete Series

Hairspray (Limited Edition Giftset)

It’s 1962, and change is in the air in Baltimore. Tracy Turnblad, a big girl with big hair and an even bigger heart, has only one passion–to dance. She wins a spot on the local TV dance program, "The Corny Collins Show" and is transformed overnight from outsider to irrepressible teen celebrity. But can the trendsetting Tracy win the heart of teen-dream Link Larkin and stand up for what she believes in, despite the program’s scheming stage manager? All she needs is her best friend Penny, a toe- tappin’ beat – and a little HAIRSPRAY!

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Hellboy Animated (Limited Edition 2-Pack with Figurine)

2 pack includes both Hellboy Sword of Storms and Hellboy Blood and Iron Includes 7 inch Hellboy Smoking Cigar Figurine with Exclusive Sword from Gentle Giant pictured.

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Tim Burton’s The Nightmare Before Christmas: Collector’s Edition – Ultimate Collector’s DVD Set + Digital Copy

Now digitally restored and re-mastered with state-of-the-art technology, The Nightmare Before Christmas: Collector s Edition is deeper, darker and more brilliant than ever as Tim Burton originally envisioned. This new version comes with Disney File Digital Copy, a full-length version of the movie you can transfer and watch on your PC, Mac, and video-enabled compatible portable players.

More info: The Nightmare Before Christmas: Collector’s Edition

Heathers – Limited Edition Box Set

This dark comedy from 1989 was a good showcase for Winona Ryder, playing a high school girl brought into a clique of bitchy classmates (all named Heather), and Christian Slater, doing his early Jack Nicholson thing. While Ryder’s character mulls over the consequences of giving up one set of friends for another, her association with a new boy (Slater) in school turns out to have deadly consequences. Director Michael Lehmann turned this unusual film into something more than another teen-death flick. There is real wit and sharp satire afoot, and the very fusion of horror and comedy is provocative in itself. Heathers remains a kind of benchmark in contemporary cinema for bringing surreal intelligence into Hollywood films. –Tom Keogh

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United Artists 30-Film Deluxe Giftset

More info: United Artists 30-Film Deluxe Giftset