JoJo's Bizarre Adventure

Seventeen-year-old Jotaro Kujo refuses to leave his jail cell, believing that an evil spirit possesses him. His grandfather, Joseph Joestar, and his friend Mohammed Abdul introduce him to spirit avatars called Stands. Later, his mother gains a Stand, and becomes sick. This is because of the vampire Dio Brando's revivification. Thus, Jotaro joins Joseph and Abdul on a trip to Egypt to defeat Dio and save his mother. (Summary by JonSmith)