Moritaka Mashiro, an average student with a talent for drawing, forgets his notebook at school, where his classmate Akito Takagi finds and looks through it. Takagi likes his drawings and asks Mashiro to team up with him to create a best-selling manga. Mashiro refuses because his uncle was a manga artist until he died from overworking, while deeply in debt, which derails his dream.

Mashiro chats with Takagi, who tells him that he chose Mashiro because he is smarter than many of his peers in matters outside of scholarship, and that he believes Azuki has a similar kind of intelligence, with the ability to be appealling to others.

Mashiro and Takagi arrive at Mashiro's uncle's apartment, where they look around and Mashiro shows Takagi the manuscripts and storyboards, that the author of a manga series produces before drawing it. Mashiro realizes that his uncle was working extremely hard until his death and vows to approach it with the same resolve.

Mashiro shows Takagi all that he has drawn and points out all the mistakes he has made, as well as the finer points of using tools for drawing manga. When Takagi questions him, Mashiro tells him about G-Pens and Kabura pens, making manuscripts, and Taro Kawaguchi's three rules to a successful manga: conceit, doing your best, and luck.

Recalling when he and Azuki turned back to look at each other at the same time, Mashiro tells Takagi that he and Azuki have been on the same frequency for years, indicating that they are connected without having to say anything about it. Azuki's best friend Kaya Miyoshi goes to Takagi to complain about him telling Azuki about her dream, and as she does so, gives indications of romantic interest in Takagi that Mashiro and Miyoshi notice.

Mashiro and Takagi meet with Akira Hattori, one of the editors at Shonen Jack. He notes that their work has flaws, as it is too text-driven and not drawn in manga style, but they have potential. He tells them that they are better suited to figuring out what could be a hit and drawing that, rather than drawing what they want, and while they are less likely to get a smash hit with that skillset, they are more likely to follow up on one if they do.

After meeting with Hattori, Mashiro and Takagi continue working on new submissions, and Mashiro writes notes to Azuki in class. Azuki cries after Mashiro asks her if they have to wait to be together until they have fulfilled their dreams, and she gives him her email.

Takagi comes up with some more ideas, including One Hundred Millionth, a story about people being ranked according to their abilities, and Hattori is impressed with the story, causing Mashiro to wonder if his art is good enough. The story is chosen as one of the finalists, but does not make it to the four chosen for the award or honorable mentions. Shortly afterward, Ishizawa, a classmate, claims that Mashiro's art is holding Takagi down. Takagi gets angry and punches Ishizawa.

Takagi is suspended for a week after punching Ishizawa, causing Mashiro to worry about him. He goes over to visit Takagi and learns that the story ideas he submitted to him were only a few of the ones he came up with. Mashiro then learns that Miyoshi and Aiko Iwase, the second best student in his grade, both have feelings for Takagi. Takagi tells them that he likes them both, but cannot be in a relationship with either due to his manga career.

Mashiro and Takagi meet with Hattori, who says the manga artists liked their work, but the editors judging it thought it would never be published. Mashiro, wanting to progress faster than he is now, wonders if he could submit a work for serialization, and Hattori is doubtful.

Mashiro and Takagi work on Money and Intelligence while applying to the relatively easy North High School. Miyoshi questions why Mashiro and Azuki are not seeing each other, and Takagi concludes that Azuki wants to remain focused on her dream.

After celebrating by eating out, Hattori, Takagi and Mashiro discuss Money and Intelligence, and what changes they need to make to it. Hattori says that they should wait until graduating from high school to go for serialization, and that even Nizuma is going for it too early.

Mashiro, at Miyoshi's suggestion, sends an email to Azuki to begin correspondence with her. During the first day of high school, Mashiro and Takagi submit their new pseudonym, "Muto Ashirogi". Hattori is impressed with their work, but Mashiro notices that he is not expecting Money and Intelligence to be serialized, wondering if it is because of his desire that they wait until after high school to get serialized.

Mashiro has come to the conclusion that doing mainstream battle manga is the way forward, and draws characters from other battle manga to polish his skills at drawing this type of manga, Meanwhile Nizuma's manga "Yellow Hit" is on the verge of being serialized, but Nizuma's editor learns that he is planning on submitting "Crow" instead, and brings him down to the editorial offices.

Hattori goes over the weaknesses of Mashiro and Takagi's storyboard, and tells them that they need good characters, simple yet exciting battles, cute heroines, and tragedy and humor to make a good storyboard. Nizuma admits that he wrote the name on the spot, rather than having it in his head, and Mashiro and Takagi realize that he is a "genius" who can draw what he wants.

Mashiro and Takagi, incorporating Hattori's suggestions, comes up with a concept for a story about an angel fighting other angels who kill humans to advance themselves, but are frustrated at their lack of progress. The name is rejected, but the feedback notes that they have promise. Around this time, Takagi is struggling to think of another idea, and begins seeing Miyoshi more often, prompting Mashiro to wonder if he is working on it at all.

Mashiro starts work as an assistant for Nizuma, and meets the other two assistants; Shinta Fukuda, who had placed lower than he did in NEXT, and Takurō Nakai, who won an award 10 years ago, but has been unable to accomplish anything noteworthy since then. Despite Fukuda and Nizuma questioning why he is working as an assistant instead of trying to get published, Mashiro is determined to learn what he can to help Takagi.

While reworking Chapter 5, Fukuda reveals that he is dissatisfied with many aspects of Jack, particularly how series are ordered by their popularity, but Yujiro tells him to get serialized before he talks about changing Jack. Nizuma tells Mashiro that he has been drawing since he was young, when his family had no money for video games, and Mashiro remembers how he also was drawing all the time before his uncle died.

Summer ends without Mashiro hearing back from Takagi, and Takagi returns the key to Mashiro's uncle's apartment, apologizing for failing to come up with a name in time but resolving to become a manga writer. Mashiro meets with Hattori, who is impressed with his idea of a detective who cons criminals into exposing themselves, but doubts he can succeed without Takagi's help.

Mashiro and Takagi discuss how to improve the concept behind the story, now known as Detective Trap, and Takagi begins looking over many detective stories that Hattori sent him. The two meet with Hattori, insisting on proceeding with Detective Trap while still in high school, and Hattori tells them that in order to get serialized, Detective Trap must do well in the Golden Cup, and they must bring him a 19-page story every two weeks to show that they can do so every week with assistants.

Mashiro and Takagi continue submitting a story every two weeks, with Mashiro sacrificing sleep to do so, but they have several weeks to go. They see Nakai with Ko Aoki, the runner-up of the Story King competition. Nakai reveals that he's entering- with her, and that Fukuda's entry is expected to place first.

Team Fukuda reaches the editorial offices, but despite their protests, the editors do not believe Koogy's advantage is unfair or his tactics are unethical, and Mashiro decides to defeat him by making a better manga. Fukuda then proposes that the authors check each other's names, and they are surprised by each other's level of skill. Midway through the session...

Mashiro and Takagi both decide to rewrite their manga. Fukuda, Aoki and Nakai also rewrite their manga. Later Fukuda's manga is shown first with positive reviews. Next Mashiro and Takagi's manga is also shown with good reviews. Nakai panics and thinks that when Nizuma said that the winners were tied and there was a third place, he meant his manga. Then Aoki and Nakai's manga is shown with also positive reviews. All three series are okayed to begin work on names for serialization.

Koogy's manga does poorly in the Golden Future Cup, leaving Mashiro and Takagi, Fukuda, and Nakai and Aoki as the top contenders. An unprecedented two-way tie happens, with Fukuda and Ashirogi Muto both getting first place. Azuki calls Takagi to thank him for supporting Mashiro and encouraging him to pursue becoming a manga artist, but is too embarrassed to congratulate Mashiro directly herself. Having won the Golden Future Cup, Mashiro and Takagi prepare to submit their story for serialization.

Thirteen series are submitted for the serialization meeting and are discussed by the team captains, editor in chief and deputy editor. Of all 13, Detective Trap and Otter 11, a manga by newcomer Kazuya Hiramaru, are chosen for serialization. Mashiro receives congratulations from his rivals, who promise to get serialized themselves to compete with him. Mashiro then reflects on how far he has come and how far he has yet to go, before he receives a call from Azuki, who congratulates ...