Sakura Dormitory is a dorm of the high school affiliated with Suimei University of the Arts (often shortened as Suiko), which hosts the strangest, most trouble-making students. After being kicked out of the normal dorm for keeping a stray cat, Sorata Kanda moves into Sakura Dormitory. As he starts to get used to the life in the dorm, Mashiro Shiina, a world famous artist who cannot even take care of her daily life, moves in. Sorata is forced to become Mashiro's handler.