Space Dandy

While I wouldn't really call it immensely hilarious, I absolutely loved the crazy plot lines and aliens this show comes up with. And even when it decides to be serious, it can hit the right notes well. Sometimes episodes aren't very good, but others like the alternate universe episode, were amazing. Not to mention that Dandy is a very colorful and memorable character in of himself, striking a good balance between a complete idiot and competent space adventurer.

s1 78.8, s2 82.6

Quality varies episode to episode, especially in the more experimental second season, but it's usually pretty fun. The characters are great and instantly memorable.